Spontaneous lipid transfer between organized lipid assemblies

Salt-induced lipid transfer between colloidal supported lipid bilayers†

Computer simulation of lipid assemblies.

Liposomes (phospholipid vesicles) have been successfully employed as drug-delivery systems and as powerful research tools for studying biomembranes I I ] . The nature of thc aggregates is known to depend on the structure of thc component lipid molecules and this relationship has prcviously been analysed in terms of mathematical models 121. As an alternative to this approach we have developed a ...

A lipid transfer protein that transfers lipid

Very few lipid transfer proteins (LTPs) have been caught in the act of transferring lipids in vivo from a donor membrane to an acceptor membrane. Now, two studies (Halter, D., S. Neumann, S.M. van Dijk, J. Wolthoorn, A.M. de Maziere, O.V. Vieira, P. Mattjus, J. Klumperman, G. van Meer, and H. Sprong. 2007. J. Cell Biol. 179:101-115; D'Angelo, G., E. Polishchuk, G.D. Tullio, M. Santoro, A.D. Cam...

Influence of membrane phospholipid composition and structural organization on spontaneous lipid transfer between membranes.

Investigations were carried out on the influence of phospholipid composition of model membranes on the processes of spontaneous lipid transfer between membranes. Acceptor vesicles were prepared from phospholipids extracted from plasma membranes of control and ras-transformed fibroblasts. Acceptor model membranes with manipulated levels of phosphatidylethanolamine (PE), sphingomyelin and phospha...

Plasma lipid transfer proteins

The composition of the plasma lipoproteins is continuously modified during their intravascular metabolism, as a result of a dynamic exchange and net transfer of lipids between particles or between particles and cells. Specialized proteins, the plasma lipid transfer proteins, facilitate the transfer and exchange of phospholipids, cholesteryl esters, and triglycerides between the lipoproteins. Al...